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Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err along the side of caution and allow FDA do its job and demand some investigation be done so your public is aware of the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on the medications. Researchers found out that participants taking this drug for the year, dropped excess weight within one month and have kept the extra weight off through the 56 weeks from the study. Contrave is really a combination with the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of many active ingredient, which might make them more effective and safer. Combo-pilling could be the newest fad or even better the newest to come under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that at the time of right now there are no long term prescription weightloss pills that have been approved by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug also can raise blood pressure and heartrate, and must not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and pulse rate and must stop used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. 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